Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

5. The 2012 Ig Nobel Chemistry Prize
The US has overtaken India as the leading user of anti-dumping and other trade defence cases, with China and its steel sector the biggest target, according to research.
4. Manufacturing won't save the economy.
近日公布的一份调查结果显示,清华大学毕业生的平均薪酬在全国高校毕业生中最高。
14. Google Calendar
在政府鼓励扩大对消费者和小企业融资的背景下,中国网上银行及P2P贷款行业迅速发展。目前中国P2P贷款领域有超过2000家公司。
你的老板有望学会使用Twitter
几乎没几个首席执行官的决策能像雅虎首席执行官玛丽莎梅耶尔禁止员工在家上班的决定那样引起了这么大的关注。这项政策出台后,人们最初的反应是它存在很大争议,而且让许多人感到不安,原因是人们认为这样的措施缺乏灵活性。
You're right to be paranoid. The company is always watching you, and there's a record of everything you do: every phone call, every text, every tweet and instant message. At most companies, they save that data forever.
To make a long story short, the Seppenwolde group went bankrupt shortly after Christmas of 1772. The disaster was a top story in Dutch newspapers. It ruined some of Amsterdam’s merchants and bankers. To prevent a general credit collapse, the city of Amsterdam stepped in temporarily as a lender of last resort. Sound familiar?
As supporters kept streaming toward the Capitol building, one yelled out, “Today, a new Puerto Rico begins!” to the cheers of others, including those holding U.S. flags.
To SKN Company in Russia for exploding old Russian ammunition and creating diamonds. Now that's recycling!
Warm hearted wishes for a happy New Year filled with all your favorite things.传统佳节之际,献上殷殷祝福,祝新年万事如意!
居民消费价格指数(CPI)继续从8月份的低点反弹,10月份,CPI同比上涨2.1%,涨幅比上月扩大0.2个百分点,并与分析师的预期中值相符。
华尔街、大街上和华盛顿的每一个人都在不断地忘记市场周期的基本原理。请记住:《笑傲股市》(How to Make Money in Stocks)作者、《投资者商务日报》(Investors Business Daily)的比尔?奥尼尔(Bill O'Neill)说,市场的上行周期平均为3.75年,下行周期平均为九个月。
Tsinghua University and Peking University are ranked in 14th and 17th place respectively -- the same positions they held in last year's rankings.
in无,fin范围-无范围的-无限的
The number of country rankings published this year rose to 42, up from 38 last year. The newly featured countries are Argentina, Mexico, Pakistan and Romania.
Hugo Boss, Chevrolet and Kleenex dropped off the list, the report said.
China has attained key targets outlined by the 12th Five-Year Plan by the end of 2015 to become a genuine giant trader, Gao said at a national meeting on commerce work.
hospitality
Rihanna vs. Rosario Dawson Both stars wore this long satin Dolce & Gabanna dress in different colors.   蕾哈娜和罗莎里奥·道森都穿了这件款式一致颜色不同的D&G
江苏、山东、浙江、河南和四川的经济总量排名紧随其后,名次与2015年相同。
It scares/intimidates people and they don't know better anyway.
For once, the Lakers are in good spot and don't have to rush into anything. Take some time. See what they have. They're not making the playoffs with that defense, but that's not really the point of this season anyway.


今年时装周预计在今年9月14日至18日举行,在此之前,由歌手帕洛玛费斯撰写并由善待动物组织出版的公开信中呼吁伦敦时装周和英国时装协会禁止动物皮草的使用。
With the second round of (re)negotiations closing on Tuesday we have truly entered the technocratic phase of these trade talks.
在全球最具价值品牌百强榜上,有15个中国品牌上榜,比去年多一个,较10年前大有增加,当时中国移动(China Mobile)是唯一上榜的中国品牌。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

据雅虎的统计,新闻取代了名人成为2010年的最热门搜索项,搜索量最大的两个新闻热点是英国石油公司的墨西哥湾漏油事件和南非世界杯足球赛。
We should stipulate at this point that neither of us have any idea how good this draft is going to be because the college season is barely underway. It sure looks nice, what with all those freshmen stacked up together in the lottery.
And while you are at it, don't forget to celebrate the imperfections. While on a 10-day trek in the Himalayas, I learned that imperfections are beautiful too. The rough edges of the mountains, the heavy hail storms in the middle of the afternoon, were "inconvenient" but added to the beauty of the trek. I am acutely aware now that in my pursuit of perfection at work, I have often failed to recognize that imperfections are also a core part of our identity that needs to be preserved and not always changed.
现在对于宣传单张的内容还没有详细的介绍,但之前投放的传单都包含谴责北韩统治者家族的言论。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

“四个全面”战略布局:全面建成小康社会是我们的战略目标,全面深化改革、全面依法治国、全面从严治党是三大战略举措

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

胡须的神奇之处
以下是我们精选的本届科隆游戏展最值得关注的新游戏。

Warm hearted wishes for a happy New Year filled with all your favorite things.传统佳节之际,献上殷殷祝福,祝新年万事如意!
In the near future, a weary Logan (Hugh Jackman) cares for an ailing Professor X (Patrick Stewart) at a remote outpost on the Mexican border. His plan to hide from the outside world gets upended when he meets a young mutant (Dafne Keen) who is very much like him. Logan must now protect the girl and battle the dark forces that want to capture her.
Will José Antonio Meade be the next president of Mexico
For the students interested in comparing school options around the world, US News released the fourth edition of its annual Best Global Universities rankings.
The 54-year-old has already said he wants Bain to be recognised as a go-to provider of digital expertise. The question is whether this will be achieved through acquisitions, poaching teams or retraining the existing workforce.
2. The 'Dad bod' is so hot right now

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


地产圈新花样 盘点“互联网+”下的新式营销


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Awards: Despite early wins for VW’s Golf GTI, the Detroit-centric jurors of the North American Car and Truck award 2015 prizes to Ford’s Mustang as well as Ford’s F-150 pickup truck.
《银河护卫队2》
8. 精彩出演)的艺术觉醒与性觉醒,欲望令她长大成人。
10月份的读数较9月份回落0.8个百分点,其中主要追踪大型国有企业的生产指数回落1.3个百分点,降至53.4。新订单指数回落1.9个百分点,降至52.9。
China's best performances by subject this year come from Tsinghua University, with three top-10 places, and Peking University, with two top-10 places. Tsinghua University finishes eighth in both Architecture/Built Environment and in Engineering (Civil and Structural). Tsinghua comes in 10th place in the world's Materials Science subject rankings.
Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.
According to China's business magazine New Fortune's 2018 Chinese wealthy list, the top 10 tycoons' total wealth reached 1.72 trillion yuan, accounting for 18% of the combined wealth of the list's total 500, and the top 10's personal wealth has surpassed 100 billion yuan for the first time.
This is the biggest question hanging over the global economy. And the biggest risk.
Taylor Swift vs. Katy Perry
Gideon Rachman

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the From 'heelgate' to the Palm Dog to the 'Dad bod' – it's been a dizzying 12 days. Here are nine lessons from the film festival as it draws to a close. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

奥巴马在俄亥俄州、威斯康星州、爱荷华州、宾夕法尼亚州和新罕布什尔州都以微弱的优势超过了罗姆尼,而在这些地方罗姆尼都曾经前往发表过演讲。根据网络数据,唯一被罗姆尼的风采征服的摇摆州是北卡罗来纳州。
卓越雇主排名:59
男性使用这个密码的几率是女性的2.8倍。
World Health Organisation declared that the cluster of microcephaly cases and other neurological disorders were a public health emergency of international concern, it was a rallying cry for the international community to respond.

The thing about the Mavericks is that this is not at all how Dirk should go out. That team has been so solid his entire career. To have a busted season now is painful. Maybe he ought to have joined Kobe, KG, and Big Fundamental last summer.

  • Only the first three authors are listed, followed by "et al."
  • 台湾群租房频发火灾 “双北”全力宣战拟拆29万户违建
  • 北京市规土委回应“欧尚欧花园”违建


遗憾的是,随着乌拉圭在当地时间周六(6月28日)被哥伦比亚淘汰出局,本届世界杯决赛将不再是巴西和乌拉圭之间的再次对话。如果巴西杀入7月13日的决赛,对手将可能是墨西哥、荷兰、哥斯达黎加、希腊、美国、比利时、阿根廷和瑞士中的一支(译注:1/8决赛中,墨西哥与希腊分别不敌荷兰与哥斯达黎加,憾别世界杯)。
您只需轻轻一挥将它们放飞,泡沫气球就会自己飘向空中。

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